Elucidating the Relationship Between ADC Measures of Cellularity and [F]FLT-PET Indications of Cellular Proliferation in a Multimodal Imaging Study of Treatment Response
نویسندگان
چکیده
Fig 3. An example of a coregistered ADC map and [F]FLT image from the center slice of a tumor (T), which both demonstrate distinct regions of heterogeneity. These preliminary coregistration studies suggest that there may be an inverse correlation between [F]FLT uptake and ADC values, particularly in highly heterogeneous tumor regions. Ongoing work is aimed at unraveling and quantifying this relationship. Fig 2. Analysis of individual mice reveals one tumor that did not demonstrate a change in [F]FLT uptake, while a separate tumor demonstrated a decreased ADC post-treatment. Elucidating the Relationship Between ADC Measures of Cellularity and [F]FLT-PET Indications of Cellular Proliferation in a Multimodal Imaging Study of Treatment Response
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